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Chirurgie laparoscopique en ambulatoire : les facteurs péri-opératoires comme le temps d’attente et l’absence de prophylaxie antiémétique favorisent la douleur et les nausées post-opératoires

Rev Esp Anestesiol Reanim. 2019 Apr;66(4):189-198. doi: 10.1016/j.redar.2018.11.007. Epub 2019 Jan 18.

Perioperative factors that contribute to postoperative pain and/or nausea and vomiting in ambulatory laparoscopic surgery.

[Article in English, Spanish]

López-Torres López J1, Piedracoba Cadahía D2, Alcántara Noalles MJ2, Simó Cortés T2, Argente Navarro P2.

Author information:
1. Servicio de Anestesiología y Reanimación, Complejo Hospitalario Universitario de Albacete, Albacete, España. Electronic address:
2. Servicio de Anestesiología y Reanimación, Hospital La Fe, Valencia, España.



Both postoperative pain and postoperative nausea and vomiting are major factors that determine the time and quality of recovery in laparoscopic surgery.


To determine the perioperative factors that contribute to the appearance of postoperative pain and postoperative nausea and vomiting in outpatient laparoscopic surgery.


A prospective study was conducted on a cohort of 297 patients undergoing laparoscopic ambulatory surgery. A record was made of preoperative factors (usual medication, anaesthetic risk, etc.), intraoperative (surgical and anaesthetic times, drugs, CO2 pressure, etc.), and postoperative factors (major and minor complications, recovery times, etc.). As dependent variables, the postoperative symptoms considered were, nausea, vomiting, and/or postoperative pain.


Considering as a combined variable the occurrence of nausea, vomiting or moderate/severe pain (4 or more points on a visual analogue scale), one or more of these symptoms occurred in 58.7% of the patients (95% CI: 52.8-64.4). Using a logistic regression, the variables associated with the appearance of symptoms were: female gender (OR: 3.4), waiting time over 45minutes prior to surgery (OR: 4.9) and no anti-emetic prophylaxis (OR: 12.2).


In patients undergoing ambulatory laparoscopic surgery, one in 4had postoperative nausea and vomiting, and approximately half of moderate-intensity pain before discharge. Considering the overall the occurrence of pain and/or postoperative níusea and vomiting, these symptoms affect more than half of the patients being operated on, and are more frequent in women and in those who have to wait to access the operating room.

Copyright © 2018 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

PMID: 30665796

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